Silver Nitrate Usage

PolyMedix Presents Data Showing Antimicrobial Activity of Sutures Containing ...

Materials are active as agents for use in antimicrobial sutures. PolyCides are synthetic antimicrobial compounds that mimic the mechanism of the host defense proteins and are being developed as additives to materials and products to make them self-sterilizing. The data was presented at the Association for Professionals in Infection Control (APIC) international meeting on June 27-29, 2011 in Baltimore, Maryland.

“There is a growing need for effective and safe alternatives to impart antimicrobial properties to medical devices,” commented, Nicholas Landekic, President and Chief Executive Officer of PolyMedix. “The currently available antimicrobial suture contains triclosan, an agent which has limited coverage and to which widespread resistance has been demonstrated. Our PolyCide biomaterials have a broad spectrum of activity and a unique mechanism of action designed to make bacterial resistance much less likely to develop. We believe that our PolyCide biomaterials could play an important role in reducing the incidence of surgical site infections, a potentially serious and expensive medical problem.”

The results, presented by Dr. Richard Scott, Vice President of Research at PolyMedix, demonstrated that the PolyCide compounds have broad spectrum activity against both Gram-positive and Gram-negative pathogens associated with surgical site infections, and have superior bacterial killing activity over triclosan and silver nitrate, another commonly used biocidal agent. Furthermore, no evidence for the development of resistance was observed with the PolyCide materials in laboratory serial passage assays, whereas resistance to triclosan was readily demonstrated.

“These data support our continued efforts to expand the use of our PolyCide compounds to other wound care applications and medical devices to improve infection control,” commented Dr. Scott. “We are excited about these results and the opportunities to develop the PolyCide materials for antimicrobial sutures.”

The PolyCide materials, like PolyMedix’s antibiotic PMX-30063 which is currently in a Phase 2 clinical trial for the treatment of Staphylococcus infections, are synthetic mimetics of the host-defense proteins, and employ the same mechanism of action that directly and selectively targets and disrupts the bacterial cell membrane. Host defense proteins represent one of the oldest and most effective antimicrobial defense systems found in humans and virtually all living creatures.

Silver Nitrate Usage - News


PolyMedix Presents Data Showing Antimicrobial Activity of Sutures Containing ...

demonstrated that the PolyCide compounds have broad spectrum activity against both Gram-positive and Gram-negative pathogens associated with surgical site infections, and have superior bacterial killing activity over triclosan and silver nitrate,



Knowledge: Islam or Western?

In Chemistry, Muslims made indelible footprints by discovering many new substances; potash, silver nitrate, corrosive sublimate and nitric and sulphuric acid Great scientific works are attributed to Khalid bin Yazid (died 708), Ja'far as-Sadiq the



Terrence Malick's Insufferable Masterpiece
Terrence Malick's Insufferable Masterpiece

Photographing the ineffable seems like a contradiction: of all the arts, the cinema depends most on the effable—on matter that reflects light, impressing itself on celluloid treated with silver nitrate or, increasingly, on bit-mapped receptors.



The Summer of Super 8: A Look at the Film's Technological Origins

At the time, standard film was 35mm wide and nitrate-based, requiring large equipment and expensive processing. It was also highly flammable. Because of this, efforts were focused on reducing the size of both film and film equipment,



Sherwood enhances Model 926 chloride analyser

in cement manufacture and, as in the food industry, Sherwood's Model 926 chloride analyser can deliver accurate results without the need to make up the fresh reagents required by traditional silver nitrate methods for chloride determination.




Make Silver Nitrate From Silver and Nitric Acid | Tips for Digital ...

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@Al3xX420 Then filter and wash, and it should be possible to re-dissolve the (now pure) silver in nitric acid and get pure silver nitrate. I haven’t tried this yet, one worry is that some copper metal may also fall off the wire so the stuff at the bottom will once again be a mixture of silver plus copper. It occurs to me that the copper would dissolve in cold nitric acid while the silver will not (much), so that might be a way of removing any copper impurities. Haven’t tried this yet.

@Al3xX420 So now we have a solution of mixed silver nitrate and copper nitrate, and we need to separate them. One way would be to place copper metal (eg electrical wire) in the solution. The copper metal exchanges places with the silver in the silver nitrate, leaving more copper nitrate in solution and silver metal crystals on the wire. They fall off if you shake it, so you get silver in the bottom. Continue until no more silver forms, and you should have all the silver at the bottom. (more)

@Al3xX420 Stirling silver is about 7% copper. The copper dissolves quite well in nitric acid. Its presence is shown by the blue color of the solution. Our source sold us a silver coin and told me it was pure silver, but my daughter noticed was stamped “stirling” on the side. So we took it back and he gave us some silver that he said was for jewelers instead. We just finished dissolving it in HNO3 and there is a light blue color, so this has copper in it, too. (Post continued.)

@NurdRage Is Nitric acid the one i need to know between real silver, fake silver and sterling silver, and the same with gold? And, how can i know when i am holding real silver? What color does it become when it is touch by nitric acid? Does fake silver become green and the same to sterling silver, and real silver become yellow or what? And what about gold? Is the same reaction?


Silver Nitrate Usage - Bookshelf

Boston medical and surgical journal

Boston medical and surgical journal

The unfortunate results which have sometimes followed the use of silver nitrate are usually due to the fact that the solution was too concentrated. ...

JAMA., The Journal of the American Medical Association

JAMA., The Journal of the American Medical Association

Mr. Higginbottom,' advocated the use of nitrate of silver in the treatment of erysipelas. He believed that with nitrate of silver, if properly applied, ...

Silver in Healthcare, Its Antimicrobial Efficacy and Safety in Use

Silver in Healthcare, Its Antimicrobial Efficacy and Safety in Use

... plant involved in the manufacture of silver nitrate and silver oxide, ... Sollemann88 listed recommendations for the use of silver nitrate and colloidal ...

The use of silver nitrate in public health dentistry, a thesis submitted in partial fulfillment ... for the degree of Master of Public Health ...

The use of silver nitrate in public health dentistry, a thesis submitted in partial fulfillment ... for the degree of Master of Public Health ...


The lancet

The lancet

Use this two or .three times and then mam to the 1 per cent, solution of silver nitrate, alternating it this time with a 10 per cent, solution of copper ...

Casual Info Directory


File:Silver-nitrate-2D.svg - Wikipedia, the free encyclopedia
Silver-nitrate-2D.svg‎ (SVG file, nominally 245 × 135 pixels, file size: 28 KB) ... Silver nitrate. Global file usage. The following other wikis use this ...

Silver Nitrate
Silver nitrate in weak solutions is used as a germicide and astringent to mucous ... INDICATIONS AND USAGE. Silver nitrate ophthalmic solution is indicated for the prevention ...

Colloidal Silver Usage Precautions
Colloidal Silver usage precautions ... avoiding the pitfalls that may accompany silver toxicity

Talk:Silver nitrate - Wikipedia, the free encyclopedia
My Dr. used silver nitrate on me yesterday during a routine visit. I just had stomach ... Silver nitrate may be corrosive, but on a scale of 1-10, 1 being ...

What Is Silver Nitrate?
Brief and Straightforward Guide: What Is Silver Nitrate? ... name from its former usage in hospitals, silver nitrate is also used for cleaning solutions and to locate ...